|
Principal characteristics of selected meta-analyses and the adjustment performed according to the "trim and fill method" |
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| Meta-analysis |
Number of trials |
Estimated number of missing studies |
Model of Effect used |
Original combined effect estimates |
Adjusted effect estimates |
Year of last trial included |
|
|
||||||
| Hofmeyr 18 |
12 |
0 |
Fixed |
0.35 (0.22–0.56) |
Unchanged |
1999 |
| Smaill 19 |
83 |
18 |
Random |
0.39 (0.35–0.43) |
0.42 (0.37–0.47) |
2001 |
| Hopkins 14 |
14 |
7 |
Fixed |
0.92 (0.70–1.23) |
0.57 (0.45–0.73)* |
1993 |
| Hopkins 20 |
11 |
3 |
Fixed |
1.08 (0.74–1.58) |
0.96 (0.68–1.36) |
1996 |
| Smaill 21 |
13 |
0 |
Fixed |
0.24 (0.19–0.32) |
Unchanged |
1987 |
| Kenyon 22 |
13 |
1 |
Fixed |
0.90 (0.74–1.10) |
0.91 (0.74–1.11) |
2001 |
| McDonald 23 |
13 |
2 |
Fixed |
0.87 (0.74–1.02) |
0.92 (0.78–1.07) |
2003 |
| Abalos 24 |
22 |
1 |
Fixed |
0.75 (0.47–1.19) |
0.73 (0.46–1.15) |
1995 |
| Knight 25 |
37 |
14 |
Fixed |
0.87 (0.80–0.94) |
0.91 (0.84–0.99) |
1999 |
| King 26 |
11 |
1 |
Fixed |
1.49 (0.67–3.34) |
1.35 (0.62–2.95) |
2002 |
| Atallah 27 |
11 |
5 |
Random |
0.35 (0.20–0.60) |
0.50 (0.32–0.78) |
2001 |
| Martin-Hirsch 13 |
11 |
3 |
Fixed |
0.28 (0.25–0.31) |
0.27 (0.25–0.30) |
1994 |
| Thacker 28 |
10 |
5 |
Fixed |
1.39 (1.21–1.59) |
1.17 (1.04–1.33) |
1993 |
| Hodnett 15 |
15 |
5 |
Fixed |
0.91 (0.83–0.99) |
0.94 (0.86–1.03)* |
2002 |
| Cheng 16 |
10 |
1 |
Fixed |
0.63 (0.44–0.92) |
0.70 (0.49–1.00)* |
2002 |
| Crowley 29 |
19 |
3 |
Fixed |
0.20 (0.06–0.70) |
0.25 (0.08–0.73) |
1992 |
| Oates-Whitehead 30 |
14 |
0 |
Fixed |
1.05 (0.83–1.34) |
Unchanged |
2002 |
| Hodnett 31 |
13 |
2 |
Fixed |
0.99 (0.90–1.09) |
0.98 (0.89–1.08) |
2001 |
| Carroli 32 |
10 |
2 |
Fixed |
0.81 (0.70–0.93) |
0.83 (0.72–0.95) |
1998 |
| Johanson 33 |
12 |
2 |
Fixed |
0.59 (0.51–0.68) |
0.60 (0.52–0.69) |
1996 |
| Hofmeyr 34 |
25 |
7 |
Random |
0.65 (0.58–0.73) |
0.72 (0.64–0.81) |
2003 |
|
* Conclusion is possibly affected by publication bias | ||||||
Souza et al. Reproductive Health 2007 4:3 doi:10.1186/1742-4755-4-3 |
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